girk|Structural mechanism underlying G protein family,project mugetsu yamamoto clan

G Protein-Coupled Inwardly-Rectifying Potassium Channels (GIRK channels) are channels found in the brain that play a crucial role in the inhibitory egirkffects of neurotransmitters.

G protein-gated inwardly rectifying potassium channel (GIRK) plays a key role in regulating neurotransmission. GIRK is opened by the direct binding of the G protein βγ subunit (Gβγ),...

The G protein-coupled inwardly rectifying potassium channels (GIRKs) are a family of lipid-gated inward-rectifier potassium ion channels which are activated (opened) by the signaligirkng lipid PIP2 and a signal transduction cascade starting with ligand -stimulated G protein-coupled receptors (GPCRs). [1][2] GPCRs in turn release activated G-protein ...

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